If you or someone you know is in crisis, contact the Military Crisis Line at 988 and press 1, or Text 838255. You can also call 911.

Signs & Symptoms of Polysubstance Abuse

Polysubstance abuse refers to the use of more than one type of drug, either at the same time or at different times, than how it was intended to be used. This form of substance abuse can increase the risk of serious health consequences. Knowing the signs and symptoms of polysubstance abuse is important for receiving proper treatment. Here are some common signs and symptoms:

Behavioral Signs

Keeping Secrets

  • Hiding drug use, lying about the amount or type of drugs used.

Changes in Social Circles

  • Meeting new friends who also use substances.
  • Withdrawing from family and longtime friends.

Ignoring Responsibilities

  • Failing to meet duties at work, school or home.

Financial Problems

  • Lack of money, borrowing or stealing money.
  • Spending large amounts of money on substances.

Legal Issues

  • Arrests for possession of illegal substance.
  • Disorderly conduct due to substance use.

Physical Signs

Changes in Appearance

  • Ignoring personal hygiene.
  • Unusual smells on breath or clothing.
  • Physical signs of injections like track marks.

Sudden Weight Changes

  • Unexpected weight loss or gain.

Unusual Pupils

  • Enlarged or small pupils.

Frequent Nosebleeds

  • Especially if related to snorted substances.

Signs of Intoxication

  • Slurred speech, poor coordination or decreased motor skills.

Psychological Signs

Mood Swings

  • Rapid and extreme changes in mood.

Irritability or Aggression

  • Unusual outbursts, aggression or irritability.

Anxiety

  • Increased anxiety or fear.

Depression

  • Sadness, loss of interest in activities or feelings of hopelessness.

Cognitive Function

  • Difficulty concentrating.
  • Memory problems and confusion.

Health Symptoms

Overdose Risk

  • Increased risk of overdose, especially when substances with similar effects are combined.

Withdrawal

  • Experiencing withdrawal symptoms from one or more substances such as headaches, nausea or chills.

Immune System

  • Increased chance of infections and illnesses due to a weakened immune system.

What to Do

If you suspect someone is struggling with polysubstance abuse, approach the situation with compassion and concern. Encourage them to seek professional help from a healthcare provider or a substance abuse treatment center. Early treatment can lead to better outcomes and help prevent the serious health conditions associated with polysubstance abuse. Learn more about prescription drug facts here.

If you or someone you know is in crisis, contact the Military Crisis Line at 988 and press 1, or Text 838255. You can also call 911.